CryoEM structure of the di-domain core of Mycobacterium tuberculosis polyketide synthase 13, essential for mycobacterial mycolic acid synthesis.
H. E. Johnston, S. M. Batt, A. K. Brown, C. G. Savva, G. M. Besra, K. Futterer
This paper reports the cryoEM structure of M. tuberculosis Pks13, revealing its homodimeric architecture and providing insights into its catalytic mechanism.
bioRxiv · Apr 28, 2024 · PreprintMicrobiology