A distinct neutrophil population invades the central nervous system during pancreatic cancer
K. G. Burfeind, X. Zhu, M. A. Norgard, P. R. Levasseur, B. Olson, K. A. Michaelis, E. R. S. Torres, S. Jeng, S. McWeeney, J. Raber, D. L. Marks
This study identifies a novel neutrophil population invading the brain during pancreatic cancer, mediated by CCR2/CCL2 and P2RX7, leading to anorexia and muscle catabolism.
bioRxiv · Jun 3, 2019 · PreprintImmunology