ImmunologyPLOS PathogensPeer-reviewed
Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer
R. Kumar, S. Deshpande, L. M. Sewall…·J. Bhattacharya
This study shows that immunization with a thermostable HIV-1 clade C Env trimer induces potent autologous neutralizing antibodies in rabbits, with distinct epitope specificity compared to natural infection.
DOI 10.1371/journal.ppat.1008977