Author

K. G. Wiman

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. Zawacka-Pankau· 1 shared Q. Zhang· 1 shared V. J. N. Bykov· 1 shared

Activity by Year

2017-2017 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperCancer Biology

J. Zawacka-Pankau

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1 paper

Recent·Most cited

APR-246 reactivates mutant p53 by targeting cysteines 124 and 277

Q. Zhang, V. J. N. Bykov, K. G. Wiman, J. Zawacka-Pankau

This study identifies cysteine residues 124 and 277 as key targets of APR-246 for reactivating mutant p53 and restoring its tumor suppressor function in cancer cells.

bioRxiv · Nov 5, 2017Cancer Biology