Single organoid RNA-sequencing reveals high organoid-to-organoid variability
K. Gehling, S. Parekh, F. Schneider, M. Kirchner, V. Kondylis, C. Nikopoulou, P. Tessarz
This study uses RNA-seq to show that organoids vary significantly between individuals within a culture, but not between batches, suggesting microenvironmental effects drive this variability.
bioRxiv · Nov 22, 2021 · PreprintCell Biology