Proteostasis collapse halts G1 progression and delimits replicative lifespan
D. F. Moreno, K. Jenkins, S. Morlot, G. Charvin, A. Csikasz-Nagy, M. Aldea
This study shows that proteostasis collapse in yeast leads to G1 arrest and limits replicative lifespan through chaperone-dependent mechanisms.
bioRxiv · May 24, 2019 · PreprintCell Biology