Toxic anti-phage defense proteins inhibited by intragenic antitoxin proteins
A. Zhong, X. Jiang, A. B. Hickman, K. Klier, G. I. C. Teodoro, F. Dyda, M. T. Laub, G. Storz
The paper identifies Rpn proteins as toxin-antitoxin systems that inhibit phage infection by blocking toxic full-length proteins with their smaller, variable C-terminal domains.
bioRxiv · May 2, 2023 · PreprintMicrobiology