A. Zhong

A robust and inducible precise genome editing via an all-in-one prime editor in human pluripotent stem cells

This paper develops an inducible prime editing system in human pluripotent stem cells that enables efficient and controllable multiplex genome editing.

Toxic anti-phage defense proteins inhibited by intragenic antitoxin proteins

The paper identifies Rpn proteins as toxin-antitoxin systems that inhibit phage infection by blocking toxic full-length proteins with their smaller, variable C-terminal domains.