Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages
S. L. Bell, K. L. Lopez, J. S. Cox, K. L. Patrick, R. O. Watson
This study identifies galectin-8 as a sensor for damaged Mtb-containing phagosomes that recruits TAX1BP1 to promote selective autophagy and control Mtb replication in macrophages.
mBio · Aug 31, 2021Peer-reviewedMicrobiology