Author

K. L. O'Brien

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

S. D. Bentley· 2 shared T. Azarian· 2 shared W. P. Hanage· 2 shared A. Ghoulia· 1 shared A. J. Pollard· 1 shared A. Skoczynska· 1 shared A. von Gottberg· 1 shared B. A. Kwambana-Adams· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersEvolutionary Biology

S. D. Bentley

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Author profile →

2 papers

Recent·Most cited

Predicting evolution using frequency-dependent selection in bacterial populations

T. Azarian, P. P. P. Martinez, B. J. Arnold, L. R. Grant, J. Corander, C. Fraser, N. Croucher, L. Hammitt, R. Reed, M. Santosham, R. R. Weatherholtz, S. D. Bentley, K. L. O'Brien, M. Lipsitch, W. P. Hanage

The paper predicts changes in pneumococcal populations after vaccination by analyzing accessory gene frequencies under negative frequency-dependent selection.

bioRxiv · Feb 25, 2020 · PreprintEvolutionary Biology

Global emergence and population dynamics of divergent serotype 3 CC180 pneumococci

T. Azarian, P. Mitchell, M. Georgieva, C. M. Thompson, A. Ghoulia, A. J. Pollard, A. von Gottberg, M. du Plessis, M. Antonio, B. A. Kwambana-Adams, S. C. Clarke, D. Everett, J. Cornick, E. Sadowy, W. Hryniewicz, , W. P. Hanage

This study analyzes global serotype 3 pneumococcal isolates to show a recent emergence of Clade II with antibiotic resistance and antigenic diversity, not linked to PCV13 usage.

bioRxiv · Jun 27, 2018Evolutionary Biology