Viral cross-linking and solid-phase purification enables discovery of ribonucleoprotein complexes on incoming RNA virus genomes
B. Kim, S. E. Arcos, K. L. Rothamel, M. Ascano
The paper introduces VIR-CLASP, a method to identify RNA virus-host protein interactions by cross-linking and solid-phase purification, and demonstrates its application with 4SU-labeled viral genomes.
bioRxiv · Apr 8, 2020Immunology