Author

M. Ascano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

B. Kim· 2 shared C. L. Wiser· 1 shared J. N. Vincent· 1 shared K. L. Rothamel· 1 shared S. E. Arcos· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersImmunology

B. Kim

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2 papers

Recent·Most cited

Viral cross-linking and solid-phase purification enables discovery of ribonucleoprotein complexes on incoming RNA virus genomes

B. Kim, S. E. Arcos, K. L. Rothamel, M. Ascano

The paper introduces VIR-CLASP, a method to identify RNA virus-host protein interactions by cross-linking and solid-phase purification, and demonstrates its application with 4SU-labeled viral genomes.

bioRxiv · Apr 8, 2020Immunology

Small molecule inhibition of human cGAS reduces total cGAMP output and cytokine expression in cells

C. L. Wiser, B. Kim, J. N. Vincent, M. Ascano

This study shows that RU.521 inhibits human and mouse cGAS, reducing cGAMP production and cytokine expression in response to dsDNA, without affecting RNA or interferon-induced responses.

bioRxiv · Mar 30, 2020Immunology