Serum from patients with Idiopathic inflammatory myopathy induces skeletal muscle weakness
C. Leijding, K. M. Andreasson, B. Horuluoglu, A. S. G. Feria, E. Van Gompel, M. Dastmalchi, S. Gastaldello, H. Alexanderson, I. E. Lundberg, D. C. Andersson
This study shows that serum from IIM patients reduces skeletal muscle force, but isolated IgG does not, suggesting humoral factors directly cause muscle weakness.
bioRxiv · Apr 2, 2024Physiology