Author

K. M. Hadden

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Vindigni· 1 shared E. Berthiaume· 1 shared J. Calvo· 1 shared J. Jackson· 1 shared K. Cong· 1 shared R. C. Dash· 1 shared S. Cantor· 1 shared S. Nayak· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

A. Vindigni

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1 paper

Recent·Most cited

Replication gaps are a cancer vulnerability counteracted by translesion synthesis

S. Nayak, J. Calvo, K. Cong, E. Berthiaume, J. Jackson, R. C. Dash, A. Vindigni, K. M. Hadden, S. Cantor

The paper identifies that oncogene expression creates replication gaps, which are suppressed by translesion synthesis (TLS), and shows that inhibiting TLS reduces cancer cell fitness.

bioRxiv · Sep 25, 2019Cancer Biology