Osteocytes remodel bone by TGF-β-induced YAP/TAZ signaling
C. D. Kegelman, J. C. Coulombe, K. M. Jordan, D. J. Horan, L. D. Qin, A. G. Robling, V. L. Ferguson, T. M. Bellido, J. D. Boerckel
This study shows YAP/TAZ signaling in osteocytes is downstream of TGF-β and controls bone remodeling by regulating matrix proteases and coordinating osteoblast/osteoclast activity.
bioRxiv · Apr 17, 2019 · PreprintCell Biology