Tau avoids the GTP cap at growing microtubule plus ends
B. T. Castle, K. M. McKibben, E. Rhoades, D. J. Odde
This paper shows that tau preferentially binds GDP-tubulin over GTP-tubulin, causing it to lag behind microtubule plus-ends and suppress shortening rather than promote growth.
iScience · Dec 1, 2020Peer-reviewedCell Biology