Author

K. Mersch

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Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2

Frequent Co-Authors

B. Nguyen· 1 shared H.-H. Lim· 1 shared J. E. Sokoloski· 1 shared J. L. Robertson· 1 shared K. Park· 1 shared R. Galletto· 1 shared T. M. Lohman· 1 shared T. N. Ozturk· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 12 mutual co-author links

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1 shared paperBiophysics

B. Nguyen

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2 papers

Recent·Most cited

Helicase Activity Promoted Through Dynamic Interactions Between a ssDNA Translocase and a Diffusing SSB Protein

K. Mersch, J. E. Sokoloski, B. Nguyen, R. Galletto, T. M. Lohman

The paper shows that Pif1 helicase uses its translocase activity to push RPA along ssDNA, disrupting duplex DNA and demonstrating a new mechanism for directional DNA unwinding.

bioRxiv · Sep 30, 2022 · PreprintBiophysics

Altering CLC stoichiometry by reducing non-polar side-chains at the dimerization interface

K. Mersch, T. N. Ozturk, K. Park, H.-H. Lim, J. L. Robertson

This study shows that non-polar side-chains at the dimerization interface of CLC-ec1 are important for dimer stability, but dimer stoichiometry depends on the solvent environment.

bioRxiv · Oct 29, 2020Biophysics