Allele-specific gene regulation, phenotypes, and therapeutic vulnerabilities in estrogen receptor alpha mutant endometrial cancer
Z. Blanchard, C. M. Rush, S. Arnesen, J. M. Vahrenkamp, A. C. Rodriguez, E. A. Jarboe, C. Brown, M. E. K. Chang, M. R. Flory, H. Mohammed, K. Modzelewska, D. H. Lum, J. Gertz
This study investigates ER mutations in endometrial cancer, showing they alter gene expression and promote cancer phenotypes, and identifies potential therapeutic targets.
bioRxiv · Jun 13, 2022Cancer Biology