HIV-specific CD8+ T-cells in tonsils express exhaustive TRM-like signatures
R. Fardoos, S. K. Nyquist, O. E. Asowata, S. W. Kazer, A. Singh, A. N. Ngoepe, J. G. Giandhari, N. M. Mthabela, D. Ramjit, S. Singh, F. Karim, S. Buus, F. Anderson, J. Z. Porterfield, A. L. Sibiya, , H. N. Kloverpris
The paper examines HIV-specific CD8+ T-cells in tonsils, finding they exhibit TRM-like exhaustion signatures compared to blood, with differences in natural HIV controllers.
bioRxiv · Nov 4, 2021 · PreprintImmunology