Phospholipase Cβ2 Promotes Vascular Endothelial Growth Factor Induced Vascular Permeability
K. N. Phoenix, Z. Yue, L. Yue, C. G. Cronin, B. T. Liang, L. H. Hoeppner, K. P. Claffey
This study identifies PLCβ2 as a key regulator of VEGF-induced vascular permeability by modulating calcium flux and PIP2 levels, showing therapeutic potential for diseases involving vascular leakage.
bioRxiv · Mar 9, 2022Cell Biology