Germline genetic determination of cancer progression and survival
B. N. Ostendorf, K. N. Tafreshian, N. Adaku, J. Bilanovic, B. Tavora, S. F. Tavazoie
This study identifies APOE germline variants as predictors of melanoma survival and progression, showing APOE2 reduces survival while APOE4 increases it, with mechanistic insights into immune and tumor cell behavior.
bioRxiv · Mar 13, 2019Cancer Biology