Author

B. N. Ostendorf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

S. F. Tavazoie· 3 shared N. Adaku· 2 shared B. Tavora· 1 shared E. S. Seltzer· 1 shared I. Keller· 1 shared J. Bilanovic· 1 shared K. N. Tafreshian· 1 shared V. Padmanaban· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 20 mutual co-author links

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3 shared papersCancer Biology

S. F. Tavazoie

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3 papers

Recent·Most cited

Neuronal substance-P drives breast cancer growth and metastasis via an extracellular RNA/TLR7 axis

V. Padmanaban, I. Keller, E. S. Seltzer, B. N. Ostendorf, Z. Kerner, S. F. Tavazoie

This study identifies neuronal substance-P as a driver of breast cancer growth and metastasis through an extracellular RNA/TLR7 signaling axis, with therapeutic targeting showing efficacy in mouse models.

bioRxiv · Mar 8, 2024 · PreprintCancer Biology

Apolipoprotein E2 Promotes Melanoma Growth, Metastasis, and Protein Synthesis via the LRP1 Receptor

N. Adaku, B. N. Ostendorf, S. F. Tavazoie

This study shows APOE2 promotes melanoma growth, metastasis, and protein synthesis via LRP1, contrasting previous findings on APOE4.

bioRxiv · Oct 3, 2022Cancer Biology

Germline genetic determination of cancer progression and survival

B. N. Ostendorf, K. N. Tafreshian, N. Adaku, J. Bilanovic, B. Tavora, S. F. Tavazoie

This study identifies APOE germline variants as predictors of melanoma survival and progression, showing APOE2 reduces survival while APOE4 increases it, with mechanistic insights into immune and tumor cell behavior.

bioRxiv · Mar 13, 2019Cancer Biology