Author

K. O'Neill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Babbage· 1 shared A. Biruete· 1 shared A. Butler· 1 shared A. C. Cheng· 1 shared A. D. Fonseca· 1 shared A. G. Lynch· 1 shared A. Lambert· 1 shared A. Saigal· 1 shared

Activity by Year

2020-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Babbage

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Novel Methylation Markers in a Prostate Cancer Cohort are Associated with Disease Development and Relapse

R. P. Lach, S. Pita, W.-K. Leung, A. Babbage, S. Merson, S. Hawkins, H. Luxton, J. Kay, H. C. Whitaker, D. J. Woodcock, V. Haberland, Z. Kote-Jarai, T. Milne-Clark, K. O'Neill, T. Brendler-Spaeth, , A. G. Lynch

The paper identifies novel methylation markers in a prostate cancer cohort associated with disease development and relapse, showing their predictive power for recurrence.

bioRxiv · Aug 27, 2026 · PreprintCancer Biology

The Dietary Fermentable Fiber Inulin Alters the Intestinal Microbiome and Improves Chronic Kidney Disease Mineral-Bone Disorder in a Rat Model of CKD

S. M. Moe, A. Biruete, N. X. Chen, C. E. Metzger, S. Srinivasan, K. O'Neill, P. Fallen, A. D. Fonseca, H. E. Wilson, P. Evenepoel, K. S. Swanson, H. de Loor, M. A. Allen

This study shows that adding inulin to the diet of CKD rats changes gut microbiota, lowers uremic toxins, and improves CKD-MBD parameters like bone and cardiovascular health.

bioRxiv · Jan 29, 2023 · PreprintCell Biology

NOVEL NUCLEAR ROLE OF HDAC6 IN PROGNOSIS AND THERAPEUTIC TARGET FOR COLORECTAL CANCER

D. J. Garcia-Dominguez, L. Hontecillas-Prieto, M. Kaliszczak, M. He, M. Burguillos, R. El Bekay, V. B. Abdul-Salam, K. Combiz, K. Shah, k. O'Neill, E. de Alava, A. Silver, N. Syed, E. O. Aboagye, N. Hajji

This study identifies a novel nuclear role of HDAC6 in colorectal cancer prognosis and therapy, showing its association with chromatin relaxation, gene expression, and synergistic effects with DNA damaging agents.

bioRxiv · Nov 2, 2020 · PreprintCancer Biology

Induction of SARS-CoV-2 protein S-specific CD8+ T cells in the lungs of gp96-Ig-S vaccinated mice

E. Fisher, L. Padula, K. Podack, K. O'Neill, M. M. Seavey, P. Jayaraman, R. Jasuja, N. Strbo

This study shows that the gp96-Ig-S vaccine induces SARS-CoV-2 protein S-specific CD8+ T cells in mice, suggesting potential for human application.

bioRxiv · Aug 24, 2020Immunology

Discovery of A New Class of Integrin Antibodies for Fibrosis

J. Zhang, T. Wang, A. Saigal, J. Johnson, J. Morrisson, S. Tabrizifard, S. A. Hollingsworth, M. J. Eddins, W. Mao, K. O'Neill, M. Garcia-Calvo, E. Carballo-Jane, D. Liu, T. Ham, Q. Zhou, , M. Handa

The paper identifies new integrin antibodies that inhibit fibrosis progression in lung injury models and show superior in vitro activity in fibroblasts.

bioRxiv · Jul 20, 2020Pharmacology & Toxicology