The splicing factor hnRNP M is a critical regulator of innate immune gene expression in macrophages
K. O. West, H. M. Scott, S. Torres-Odio, A. P. West, K. Patrick, R. O. Watson
This study shows that hnRNP M represses innate immune gene expression in macrophages and its phosphorylation by pathogen sensing cascades regulates splicing to control immune responses.
bioRxiv · Apr 30, 2019Immunology