Author

K. Pestal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

B. Wienert· 1 shared E. Zelin· 1 shared G. Barton· 1 shared J. E. Corn· 1 shared J. Shin· 1 shared L. Slayden· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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1 shared paperCell Biology

B. Wienert

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2 papers

Recent·Most cited

Kruppel-like Factor (KLF) family members control expression of genes required for serous cavity and alveolar macrophage identities

K. Pestal, L. Slayden, G. Barton

The paper identifies KLF2 and KLF4 as regulators of serous cavity and alveolar macrophage identities through direct gene regulation.

bioRxiv · Feb 28, 2024Immunology

In vitro transcribed guide RNAs trigger an innate immune response via the RIG-I pathway

B. Wienert, J. Shin, E. Zelin, K. Pestal, J. E. Corn

The paper shows that in vitro transcribed guide RNAs trigger a strong innate immune response via the RIG-I pathway when used in CRISPR-Cas9 RNP editing of primary cells.

bioRxiv · Mar 3, 2018Cell Biology