OCA-B/Pou2af1 is sufficient to promote CD4+ T cell memory and prospectively identifies memory precursors
W. Sun, E. P. Hughes, H. Kim, J. Perovanovic, K. R. Charley, B. Perkins, J. Du, A. Ibarra, A. R. Syage, J. S. Hale, M. A. Williams, D. Tantin
This study shows that OCA-B expression promotes CD4+ T cell memory and identifies memory precursor cells using a reporter mouse line.
Proceedings of the National Academy of Sciences · Feb 27, 2024Peer-reviewedImmunology