E. P. Hughes

OCA-B/Pou2af1 is sufficient to promote CD4+ T cell memory and prospectively identifies memory precursors

This study shows that OCA-B expression promotes CD4+ T cell memory and identifies memory precursor cells using a reporter mouse line.

OCA-B promotes pathogenic maturation 1 of stem-like CD4+ T cells and autoimmune demyelination

This study identifies OCA-B as a driver of pathogenic maturation in stem-like CD4+ T cells, promoting autoimmune demyelination in multiple sclerosis.