Cell BiologybioRxiv
Stable transplantation of human mitochondrial DNA by high-throughput, pressurized mitochondrial delivery
A. J. Sercel, A. N. Patananan, T. Man…·M. A. Teitell
This paper develops MitoPunch, a device for delivering mitochondria to cells, enabling stable retention of exogenous mtDNA and creating SIMR cells with specific mtDNA-nDNA combinations.
DOI 10.7554/elife.63102