Author

A. J. Sercel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. K. Yu· 1 shared A. N. Patananan· 1 shared C. P. Kempes· 1 shared D. Gallagher· 1 shared E. D. Shaulson· 1 shared G. Sturm· 1 shared G. W. Guyot· 1 shared H. Pontzer· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

A. K. Yu

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2 papers

Recent·Most cited

Accelerated physiology and increased energy expenditure in animals and humans with mitochondrial defects: A meta-analysis

A. J. Sercel, G. Sturm, E. D. Shaulson, D. Gallagher, M.-P. St-Onge, C. P. Kempes, H. Pontzer, M. Hirano, M. Picard

This study meta-analyzes energy expenditure in mitochondrial defect models, finding elevated energy costs in 51% of animal studies and similar trends in humans, suggesting hypermetabolism.

bioRxiv · Sep 9, 2023 · PreprintCell Biology

Stable transplantation of human mitochondrial DNA by high-throughput, pressurized mitochondrial delivery

A. J. Sercel, A. N. Patananan, T. Man, T.-H. Wu, A. K. Yu, G. W. Guyot, S. Rabizadeh, K. R. Niazi, P.-Y. Chiou, M. A. Teitell

This paper develops MitoPunch, a device for delivering mitochondria to cells, enabling stable retention of exogenous mtDNA and creating SIMR cells with specific mtDNA-nDNA combinations.

bioRxiv · Sep 15, 2020Cell Biology