The impact of purifying and background selection on the inference of population history: problems and prospects
P. Johri, K. Riall, H. Becher, L. Excoffier, B. Charlesworth, J. D. Jensen
This paper examines how purifying and background selection affect population history inference, showing biases in demographic estimates and proposing a correction method using the distribution of fitness effects.
bioRxiv · Apr 28, 2020Evolutionary Biology