Alternative transcription cycle for bacterial RNA polymerase
T. T. Harden, K. S. Herlambang, M. Chamberlain, J.-B. Lalanne, C. D. Wells, G.-W. Li, R. Landick, A. Hochschild, J. Kondev, J. Gelles
The paper observes bacterial RNA polymerase (RNAP) remaining bound to DNA after termination and restarting transcription in reverse, producing antisense transcripts, using single-molecule fluorescence microscopy and genome-wide RNA sequencing.
bioRxiv · Jun 11, 2019Biophysics