Author

K. S. Koch

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:rat· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

H. L. Leffert· 2 shared T. Moran· 2 shared W. T. Shier· 2 shared

Activity by Year

2017-2017 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersCancer Biology

H. L. Leffert

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2 papers

Recent·Most cited

N-acetyl-2-aminofluorene (AAF) processing in adult rat hepatocytes in primary culture occurs by high-affinity low-velocity and low-affinity high-velocity AAF metabolite-forming systems

K. S. Koch, T. Moran, W. T. Shier, H. L. Leffert

This study investigates AAF metabolism in adult rat hepatocytes, identifying two main metabolic systems and their kinetic parameters.

bioRxiv · Dec 19, 2017Cancer Biology

High-affinity low-capacity and low-affinity high-capacity N-acetyl-2-aminofluorene (AAF) macromolecular binding sites are revealed during the growth cycle of adult rat hepatocytes in primary culture

K. S. Koch, T. Moran, W. T. Shier, H. L. Leffert

This study identifies two AAF metabolite binding sites in rat hepatocytes during the growth cycle, with different affinities and capacities, and links them to DNA and cytoplasmic proteins.

bioRxiv · Dec 19, 2017Cancer Biology