Single-molecule visualization of stalled replication-fork rescue by the Escherichia coli Rep helicase
K. S. Whinn, Z.-Q. Xu, S. Jergic, N. Sharma, L. M. Spenkelink, N. E. Dixon, A. M. van Oijen, H. Ghodke
This study visualizes how the Escherichia coli Rep helicase rescues stalled replication forks by removing roadblocks, showing replication restart is the rate-limiting step.
bioRxiv · Dec 4, 2022 · PreprintBiochemistry