Cell BiologybioRxiv
Nucleolar TFIIE plays a role in ribosomal biogenesis and performance
T. Phan, P. Maity, C. Ludwig…·S. Iben
This study identifies TFIIE's role in ribosomal RNA synthesis and shows that mutations impair ribosomal biogenesis, leading to proteostasis loss and TTD symptoms.
DOI 10.1093/nar/gkab866