Narrow equilibrium window for complex coacervation of tau and RNA under cellular conditions
Y. Lin, J. McCarty, J. N. Rauch, K. T. Delaney, K. S. Kosik, G. H. Fredrickson, J.-E. Shea, S. Han
This study identifies the narrow conditions under which tau and RNA form reversible coacervates and fibrils, revealing entropy-driven LLPS under physiological conditions.
bioRxiv · Sep 22, 2018Biophysics