Author

K. W. Brown

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Zahed· 1 shared D. Lee· 1 shared D. Legge· 1 shared J. Barratt· 1 shared K. Malik· 1 shared K. Pritchard-Jones· 1 shared L. Ling· 1 shared L. Panousopoulus· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Zahed

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1 paper

Recent·Most cited

The epithelial splicing regulator ESRP2 is epigenetically repressed by DNA hypermethylation in Wilms tumour and acts as a tumour suppressor

D. Legge, L. Ling, W. Moriarty, D. Lee, M. Szemes, A. Zahed, L. Panousopoulus, W. Y. Chung, Y. Aghabi, J. Barratt, R. Williams, K. Pritchard-Jones, K. Malik, S. Oltean, K. W. Brown

This study identifies ESRP2 as an epigenetically repressed tumour suppressor in Wilms tumour through DNA hypermethylation, showing its ability to inhibit proliferation and suppress tumour growth.

bioRxiv · Nov 2, 2020Cancer Biology