TPR1, a novel rifampin derivative demonstrates efficacy alone and in combination with doxycycline against the NIAID Category A Priority Pathogen F. tularensis
J. E. Cummings, K. W. Slayden, R. A. Slayden
This study evaluates the efficacy of TPR1, a rifampin derivative, against F. tularensis both alone and in combination with doxycycline, showing reduced bacterial burden and 100% survival in mice.
bioRxiv · Feb 12, 2021Microbiology