Author

R. A. Slayden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

J. E. Cummings· 2 shared A. C. Fagre· 1 shared A. S. Latham· 1 shared C. C. Dawson· 1 shared C. P. McDermott· 1 shared J. Lewis· 1 shared K. A. Popichak· 1 shared K. W. Slayden· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

J. E. Cummings

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A novel glucocorticoid and androgen receptor modulator reduces viral entry and innate immune inflammatory responses in the Syrian Hamster model of SARS-CoV-2

S. M. Rocha, A. C. Fagre, A. S. Latham, K. A. Popichak, C. P. McDermott, C. C. Dawson, J. Lewis, P. Reigan, T. A. Aboellail, R. C. Kading, T. Schountz, N. D. Theise, R. A. Slayden, R. B. Tjalkens

This paper shows that PT150, a glucocorticoid and androgen receptor antagonist, reduces SARS-CoV-2 replication and inflammatory responses in Syrian hamsters.

bioRxiv · Feb 20, 2021Immunology

TPR1, a novel rifampin derivative demonstrates efficacy alone and in combination with doxycycline against the NIAID Category A Priority Pathogen F. tularensis

J. E. Cummings, K. W. Slayden, R. A. Slayden

This study evaluates the efficacy of TPR1, a rifampin derivative, against F. tularensis both alone and in combination with doxycycline, showing reduced bacterial burden and 100% survival in mice.

bioRxiv · Feb 12, 2021Microbiology

Profiling susceptibility of NIAID Category A and B priority and emerging pathogens to define strain panels for drug discovery and active drug classes

J. E. Cummings, Z. Abdo, R. A. Slayden

The paper assesses drug susceptibility of NIAID priority pathogens to standard of care drugs, identifies non-redundant strain panels, and classifies pharmacophores for drug discovery.

bioRxiv · Dec 4, 2020 · PreprintMicrobiology