Radial glia promote microglial development through integrin aVb8 -TGFb1 signaling
G. L. McKinsey, N. Santander, X. Zhang, K. Kleemann, L. Tran, A. Katewa, K. Conant, M. Barraza, K. Waddell, C. O. Lizama, M. La Russa, J. H. Koo, H. Lee, D. Mukherjee, H. Paidassi, , T. D. Arnold
This study shows radial glia use integrin aVb8-TGFb1 signaling to promote microglial development, with disruptions causing dysmature microglia and neuromotor symptoms.
bioRxiv · Jul 13, 2023Immunology