CD117/c-kit Represents a Prostate Cancer Stem-Like Subpopulation Driving Progression, Migration, and TKI Resistance
K. Harris, L. Shi, B. Foster, M. Mobley, P. Elliott, C. Song, K. Watabe, C. Langefeld, B. Kerr
This study shows CD117/c-kit expression in prostate cancer cells correlates with poor survival and promotes aggressiveness, migration, and TKI resistance through CSC-like properties.
bioRxiv · Feb 25, 2020Cancer Biology