B. Kerr

Division of labor promotes the entrenchment of multicellularity

This study shows that division of labor in digital multicells stabilizes multicellularity by increasing fitness compared to unicellular revertants.

Evolutionary crowdsourcing: alignment of fitness landscapes allows cross-species adaptation of a horizontally transferred gene

The paper examines how horizontal gene transfer affects gene evolution across species by aligning fitness landscapes and shows that adaptive evolution in one species can translate to another.

The cost of information acquisition by natural selection

This paper challenges Kimura's theory on the cost of information acquisition by natural selection using experimental evolution of E. coli and computational learning theory.

Evolution with private resources reverses some changes from long-term evolution with public resources

The paper shows that mutations from evolving under shared resources can enable reversion to ancestral phenotypes when selection shifts to favor numerical yield.

Host-parasite coevolution promotes innovation through deformations in fitness landscapes

The paper tests how coevolution between a virus and its bacterial host affects the likelihood of evolutionary innovation by altering fitness landscapes.

CD117/c-kit Represents a Prostate Cancer Stem-Like Subpopulation Driving Progression, Migration, and TKI Resistance

This study shows CD117/c-kit expression in prostate cancer cells correlates with poor survival and promotes aggressiveness, migration, and TKI resistance through CSC-like properties.

Estimating the rate of plasmid transfer with an adapted Luria-Delbrück fluctuation analysis

This paper introduces a new method to estimate plasmid transfer rates between bacterial cells, showing it is more accurate than existing methods.

The proteasomal deubiquitinating enzyme PSMD14 regulates macroautophagy by controlling Golgi-to-ER retrograde transport

The paper identifies PSMD14 as a regulator of Golgi-to-ER retrograde transport and macroautophagy through its role in K63-Ub chain deubiquitination.

Kindlin-3 Mutation in Mesenchymal Stem Cells Results in Enhanced Chondrogenesis

This study shows Kindlin-3 promotes chondrogenesis by regulating integrin activation and SOX9 expression in mesenchymal stem cells.

C-terminal HSP90 Inhibitors Block the HSP90:HIF-1a Interaction and Inhibit the Cellular Hypoxic Response

This study shows C-terminal HSP90 inhibitors block HIF-1 stabilization under hypoxia, leading to HIF-1 degradation and reduced hypoxic gene expression in colorectal cancer cells.

Adaptations of an RNA virus to increasing thermal stress

This study evolves an RNA virus under different thermal stress regimes and finds that gradual temperature increases lead to better initial survival at high temperatures, though final survival and mutation rates are not significantly affected.