Spotiphy enables single-cell spatial whole transcriptomics across the entire section
Jiyuan Yang, Ziqian Zheng, Yun Jiao, Kaiwen Yu, Sheetal Bhatara, Xu Yang, Sivaraman Natarajan, Jiahui Zhang, Qingfei Pan, John B. Easton, Koon‐Kiu Yan, Junmin Peng, Kaibo Liu, Jiyang Yu
Spotiphy transforms spatial transcriptomics data into single-cell-resolved whole-transcriptome images, revealing novel cellular compositions and spatial domains in Alzheimer's and breast tissue.
Nature Methods · Mar 12, 2025Peer-reviewedSystems Biology