Cancer-associated nucleolar morphological changes coincide with altered subcompartment organization and accelerated nascent rRNA trafficking in breast cancer cells
Kaidi Fan, Wenhao Wang, Gideon Kipkemoi, Yangdulin Li, Yutaka Kikuchi, Haruko Takahashi
This study compares nucleolar morphology, subcompartment organization, and rRNA dynamics between normal and breast cancer cells, showing that cancer-associated changes are reversible and involve multiple dimensions.
bioRxiv · Sep 23, 2026 · PreprintCancer Biology