Haruko Takahashi

Mouse suppressyn-like 1 suppresses membrane fusion through envelope glycoprotein recognition

This paper identifies mSUPYNL1 as a retrovirus-derived protein that suppresses membrane fusion through direct recognition of envelope glycoproteins, distinct from receptor interference mechanisms.

Cancer-associated nucleolar morphological changes coincide with altered subcompartment organization and accelerated nascent rRNA trafficking in breast cancer cells

This study compares nucleolar morphology, subcompartment organization, and rRNA dynamics between normal and breast cancer cells, showing that cancer-associated changes are reversible and involve multiple dimensions.

Identification of anisotropy in chromosome dynamics by principal component analysis using integrated spatial genomics

The paper uses principal component analysis on spatial genomics data to identify isotropic and anisotropic modes of chromosome fluctuations in mouse embryonic stem cells.

Identification of transcription termination defects at DNA hypomethylated transcription termination sites in DNA methyltransferase 3a-deficient vertebrates.

The paper identifies transcription termination defects at hypomethylated TTSs in Dnmt3a-deficient vertebrates using methylome and transcriptome data.