Author

Yutaka Kikuchi

Hiroshima UniversityORCID 0000-0001-5688-7358Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Haruko TakahashiiD· 3 shared Akinori AwazuiD· 2 shared Takuya NaraiD· 2 shared Gideon KipkemoiiD· 1 shared Kaidi Fan· 1 shared Kazuya Takayama· 1 shared Masaki ShiraiiD· 1 shared Masashi FujiiiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

Haruko TakahashiORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 23, 2026

Cancer-associated nucleolar morphological changes coincide with altered subcompartment organization and accelerated nascent rRNA trafficking in breast cancer cells

Kaidi Fan, Wenhao Wang, Gideon Kipkemoi…·Haruko Takahashi

This study compares nucleolar morphology, subcompartment organization, and rRNA dynamics between normal and breast cancer cells, showing that cancer-associated changes are reversible and involve multiple dimensions.

DOI 10.64898/2026.09.22.753621

humanexperimental assay

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BioinformaticsbioRxivPreprintJan 27, 2024

Identification of anisotropy in chromosome dynamics by principal component analysis using integrated spatial genomics

Takuya Nara, Haruko Takahashi, Akinori Awazu, Yutaka Kikuchi

The paper uses principal component analysis on spatial genomics data to identify isotropic and anisotropic modes of chromosome fluctuations in mouse embryonic stem cells.

DOI 10.1101/2024.01.27.577362

mousespatial transcriptomics

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GenomicsbioRxivPreprintJun 30, 2021

Identification of transcription termination defects at DNA hypomethylated transcription termination sites in DNA methyltransferase 3a-deficient vertebrates.

Masaki Shirai, Takuya Nara, Haruko Takahashi…·Yutaka Kikuchi

The paper identifies transcription termination defects at hypomethylated TTSs in Dnmt3a-deficient vertebrates using methylome and transcriptome data.

1 citation

mousezebrafish

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