Electrical synapse formation is differentially regulated by distinct isoforms of a postsynaptic scaffold
Jennifer J. Carlisle Michel, Margaret M. B. Grivette, Amber T. Harshfield, Lisa Huynh, Ava P. Komons, Bradley Loomis, Kaitlan McKinnis, Brennen T. Miller, Ethan Q. Nguyen, Tiffany W. Huang, Sophia Lauf, Elias S. Michel, Mia E. Michel, Audrey J. Marsh, Lila E. Kaye, , Adam C. Miller
The paper shows that different isoforms of the ZO1b gene contribute uniquely to the electrical synapse density complex, affecting gap junction channel localization and function in zebrafish.
bioRxiv · Jun 27, 2022 · PreprintNeuroscience