Adam C. Miller

This study presents the first chromosome-scale genome of a female California two-spot octopus, revealing a ZO sex chromosome system and demonstrating the ancient origin of the sex chromosome in cephalopods.

The paper identifies hundreds of Connexin-associated proteins in zebrafish electrical synapses, revealing molecular diversity and overlap with chemical synapse proteomes, and links these proteins to neurological disorders.

This study identifies the C-terminal region of Cx36 as critical for its transport from the ER to the Golgi via interactions with COPII and Grasp55.

This study identifies Neurobeachin's role in restricting electrical synapse proteins to dendrites in zebrafish neurons.

The paper presents a single-cell molecular atlas of the octopus optic lobe, identifying neuronal and non-neuronal cell types and their spatial organization.

The paper shows that different isoforms of the ZO1b gene contribute uniquely to the electrical synapse density complex, affecting gap junction channel localization and function in zebrafish.

The paper identifies a mutation in tjp1b that disrupts electrical synapse formation in zebrafish by preventing neural gap junction channel localization.

The paper maps the spatial and temporal expression of connexin genes in zebrafish during organogenesis, revealing tissue- and cell-type-specific patterns and providing a guide for human connexin genes.

The paper shows that ZO1, a scaffolding protein, is required for Connexin localization at electrical synapses, which is necessary for functional gap junctions and synaptic transmission.

This study presents a single-cell transcriptomic atlas of zebrafish lens development, identifying novel regulators and expression patterns of crystallin and other genes.

The paper shows how stochastic and stereotyped transcription factor interactions regulate photoreceptor subtype fate in Drosophila.

The paper identifies zebrafish orthologs of the RAAS system and shows they are expressed in a specific intestinal cell type relevant to COVID-19 comorbidities.

This paper creates a single-cell transcriptome atlas of zebrafish development, identifying 220 cell clusters and providing gene expression insights across four days of development.

The paper identifies Tjp1b as an intracellular scaffold required for electrical synapse formation and shows its asymmetric localization and function at the postsynaptic side.

The paper identifies a genetic basis for molecular asymmetry at vertebrate electrical synapses in zebrafish, showing that two Connexins function presynaptically and postsynaptically, respectively, and are required for escape responses.