NeuroscienceJournal of NeurophysiologyPeer-reviewed
Simulated ischemia in live cerebral slices is mimicked by opening the Na+/K+ pump: clues to the generation of spreading depolarization.
Danielle H.J. Kim, Peter J. Gagolewicz, Sydney Amelia McQueen…·R. David Andrew
The paper shows that palytoxin mimics ischemia-induced spreading depolarization in brain slices by activating the Na+/K+ pump, suggesting a potential therapeutic target for ischemic brain injury.
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