New inhibitors of the Pseudomonas aeruginosa enzyme, PqsE, and methods assessing their potential to induce a conformational change via active site binding
Samantha B. Orr, Hannah A. Jones, Margaret G. O’Hara, Kaitlyn R. Smith, Isabelle R. Taylor
This study designs and evaluates new inhibitors of PqsE, an enzyme in P. aeruginosa, to disrupt its interaction with RhlR and reduce virulence.
mSphere · Apr 20, 2026Peer-reviewedBiochemistry