Functional Validation of SAM Riboswitch Element A from Listeria monocytogenes
Ian Hall, Kaitlyn Zablock, Raeleen Sobetski, Chase A. Weidmann, Sarah C. Keane
The paper validates SreA as a functional SAM-I riboswitch in Listeria monocytogenes through ligand binding, structure, and transcription assays, showing it binds SAM at lower concentrations than other SAM riboswitches but does not terminate transcription.
Biochemistry · Sep 26, 2024Peer-reviewedBiochemistry